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Isogenic mice exhibit sexually-dimorphic DNA methylation patterns across multiple tissues
BACKGROUND: Cytosine methylation is a stable epigenetic modification of DNA that plays an important role in both normal physiology and disease. Most diseases exhibit some degree of sexual dimorphism, but the extent to which epigenetic states are influenced by sex is understudied and poorly understoo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729250/ https://www.ncbi.nlm.nih.gov/pubmed/29237414 http://dx.doi.org/10.1186/s12864-017-4350-x |