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Redundancy analysis allows improved detection of methylation changes in large genomic regions
BACKGROUND: DNA methylation is an epigenetic process that regulates gene expression. Methylation can be modified by environmental exposures and changes in the methylation patterns have been associated with diseases. Methylation microarrays measure methylation levels at more than 450,000 CpGs in a si...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729265/ https://www.ncbi.nlm.nih.gov/pubmed/29237399 http://dx.doi.org/10.1186/s12859-017-1986-0 |