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Quantification of sterol-specific response in human macrophages using automated imaged-based analysis

BACKGROUND: The transformation of normal macrophage cells into lipid-laden foam cells is an important step in the progression of atherosclerosis. One major contributor to foam cell formation in vivo is the intracellular accumulation of cholesterol. METHODS: Here, we report the effects of various com...

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Detalles Bibliográficos
Autores principales: Gater, Deborah L., Widatalla, Namareq, Islam, Kinza, AlRaeesi, Maryam, Teo, Jeremy C. M., Pearson, Yanthe E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729278/
https://www.ncbi.nlm.nih.gov/pubmed/29237459
http://dx.doi.org/10.1186/s12944-017-0629-9