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Quantification of sterol-specific response in human macrophages using automated imaged-based analysis
BACKGROUND: The transformation of normal macrophage cells into lipid-laden foam cells is an important step in the progression of atherosclerosis. One major contributor to foam cell formation in vivo is the intracellular accumulation of cholesterol. METHODS: Here, we report the effects of various com...
Autores principales: | Gater, Deborah L., Widatalla, Namareq, Islam, Kinza, AlRaeesi, Maryam, Teo, Jeremy C. M., Pearson, Yanthe E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729278/ https://www.ncbi.nlm.nih.gov/pubmed/29237459 http://dx.doi.org/10.1186/s12944-017-0629-9 |
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