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A network-based predictive gene-expression signature for adjuvant chemotherapy benefit in stage II colorectal cancer

BACKGROUND: The clinical benefit of adjuvant chemotherapy for stage II colorectal cancer (CRC) is controversial. This study aimed to explore novel gene signature to predict outcome benefit of postoperative 5-Fu-based therapy in stage II CRC. METHODS: Gene-expression profiles of stage II CRCs from tw...

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Detalles Bibliográficos
Autores principales: Cao, Bangrong, Luo, Liping, Feng, Lin, Ma, Shiqi, Chen, Tingqing, Ren, Yuan, Zha, Xiao, Cheng, Shujun, Zhang, Kaitai, Chen, Changmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729289/
https://www.ncbi.nlm.nih.gov/pubmed/29237416
http://dx.doi.org/10.1186/s12885-017-3821-4