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Necessity to evaluate PI3K/Akt signalling pathway in proarrhythmia

The incidence of QT prolongation and torsades de pointes is on the rise due to the use of cardiovascular and non-cardiovascular drugs. Robust efforts have been made and are still ongoing to understand the underlying mechanisms that can enhance or prevent the development of drug-induced proarrhythmia...

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Detalles Bibliográficos
Autores principales: Ezeani, Martin, Elom, Sunday
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729307/
https://www.ncbi.nlm.nih.gov/pubmed/29259786
http://dx.doi.org/10.1136/openhrt-2017-000596