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Control of amino acid transport coordinates metabolic reprogramming in T-cell malignancy

This study explores the regulation and importance of System L amino acid transport in a murine model of T-cell acute lymphoblastic leukemia (T-ALL) caused by deletion of phosphatase and tensin homolog deleted on chromosome 10 (PTEN). There has been a strong focus on glucose transport in leukemias bu...

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Detalles Bibliográficos
Autores principales: Grzes, K M, Swamy, M, Hukelmann, J L, Emslie, E, Sinclair, L V, Cantrell, D A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729345/
https://www.ncbi.nlm.nih.gov/pubmed/28546582
http://dx.doi.org/10.1038/leu.2017.160