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Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis

BACKGROUND: Meta-analysis shows that women with diabetes have a 20% increased risk of breast cancer and also an increased risk for distant metastasis and mortality. The molecular mechanisms for distant metastasis and mortality in breast cancer patients with diabetes are not very well understood. MET...

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Detalles Bibliográficos
Autores principales: Nandy, Sushmita Bose, Orozco, Alexis, Lopez-Valdez, Rebecca, Roberts, Rene, Subramani, Ramadevi, Arumugam, Arunkumar, Dwivedi, Alok Kumar, Stewart, Viktoria, Prabhakar, Gautham, Jones, Stephanie, Lakshmanaswamy, Rajkumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729435/
https://www.ncbi.nlm.nih.gov/pubmed/29024936
http://dx.doi.org/10.1038/bjc.2017.335