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In-depth proteomic analysis of tissue interstitial fluid for hepatocellular carcinoma serum biomarker discovery

BACKGROUND: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. New serum biomarkers for HCC screening are needed, especially for alpha-fetoprotein (AFP) negative patients. As a proximal fluid between body fluids and intracellular fluid, tissue interstitial fluid (TIF) is a suitable...

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Hao, Ning, Liu, Wei, Lu, Min, Sun, Longqin, Chen, Ning, Wu, Miantao, Zhao, Xiaohang, Xing, Baocai, Sun, Wei, He, Fuchu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729441/
https://www.ncbi.nlm.nih.gov/pubmed/29024941
http://dx.doi.org/10.1038/bjc.2017.344