ANO9/TMEM16J promotes tumourigenesis via EGFR and is a novel therapeutic target for pancreatic cancer

BACKGROUND: Anoctamin (ANO)/transmembrane member 16 (TMEM16) proteins mediate diverse physiological and pathophysiological functions including cancer cell proliferation. The present study aimed to identify the role of ANOs in pancreatic cancer. METHODS: In an initial screen of ANOs, ANO9/TMEM16J was...

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Detalles Bibliográficos
Autores principales: Jun, Ikhyun, Park, Hyung Soon, Piao, He, Han, Jung Woo, An, Min Ji, Yun, Byeong Gyu, Zhang, Xianglan, Cha, Yong Hoon, Shin, You Keun, Yook, Jong In, Jung, Jinsei, Gee, Heon Yung, Park, Joon Seong, Yoon, Dong Sup, Jeung, Hei-Cheul, Lee, Min Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729472/
https://www.ncbi.nlm.nih.gov/pubmed/29024940
http://dx.doi.org/10.1038/bjc.2017.355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729472/
https://www.ncbi.nlm.nih.gov/pubmed/29024940
http://dx.doi.org/10.1038/bjc.2017.355

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