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CXCR4/CXCR7/CXCL12 axis promotes an invasive phenotype in medullary thyroid carcinoma

BACKGROUND: Medullary thyroid carcinoma (MTC) is a rare and challenging endocrine malignancy. Once spread, the therapeutic options are limited and the outcome poor. For these patients, the identification of new druggable biological markers is of great importance. Here, we investigated the prognostic...

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Detalles Bibliográficos
Autores principales: Werner, Thomas A, Forster, Christina M, Dizdar, Levent, Verde, Pablo E, Raba, Katharina, Schott, Matthias, Knoefel, Wolfram T, Krieg, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729476/
https://www.ncbi.nlm.nih.gov/pubmed/29112684
http://dx.doi.org/10.1038/bjc.2017.364