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Evaluation of epidermal growth factor receptor signaling effects in gastric cancer cell lines by detailed motility-focused phenotypic characterization linked with molecular analysis

BACKGROUND: Gastric cancers frequently overexpress the epidermal growth factor receptor (EGFR), which has been implicated in pathological processes including tumor cell motility, invasion and metastasis. Targeting EGFR with the inhibitory antibody cetuximab may affect the motile and invasive behavio...

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Detalles Bibliográficos
Autores principales: Keller, Simone, Kneissl, Julia, Grabher-Meier, Verena, Heindl, Stefan, Hasenauer, Jan, Maier, Dieter, Mattes, Julian, Winter, Peter, Luber, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729506/
https://www.ncbi.nlm.nih.gov/pubmed/29237412
http://dx.doi.org/10.1186/s12885-017-3822-3