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Necroptosis in microglia contributes to neuroinflammation and retinal degeneration through TLR4 activation

Inflammation has emerged to be a critical mechanism responsible for neural damage and neurodegenerative diseases. Microglia, the resident innate immune cells in retina, are implicated as principal components of the immunological insult to retinal neural cells. The involvement of microglia in retinal...

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Detalles Bibliográficos
Autores principales: Huang, Zijing, Zhou, Tian, Sun, Xiaowei, Zheng, Yingfeng, Cheng, Bing, Li, Mei, Liu, Xialin, He, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729519/
https://www.ncbi.nlm.nih.gov/pubmed/28885615
http://dx.doi.org/10.1038/cdd.2017.141