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Necroptosis in microglia contributes to neuroinflammation and retinal degeneration through TLR4 activation
Inflammation has emerged to be a critical mechanism responsible for neural damage and neurodegenerative diseases. Microglia, the resident innate immune cells in retina, are implicated as principal components of the immunological insult to retinal neural cells. The involvement of microglia in retinal...
Autores principales: | Huang, Zijing, Zhou, Tian, Sun, Xiaowei, Zheng, Yingfeng, Cheng, Bing, Li, Mei, Liu, Xialin, He, Chang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729519/ https://www.ncbi.nlm.nih.gov/pubmed/28885615 http://dx.doi.org/10.1038/cdd.2017.141 |
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