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Anti-apoptotic BCL-2 family members in development

Almost 30 years ago it was first appreciated that anti-apoptotic B-cell lymphoma-2 (BCL-2) prevents the induction of apoptosis not only in malignant cells, but also in normal cellular lineages. This critical observation has rapidly evolved from merely identifying new BCL-2 family members to understa...

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Detalles Bibliográficos
Autores principales: Opferman, Joseph T, Kothari, Anisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729530/
https://www.ncbi.nlm.nih.gov/pubmed/29099482
http://dx.doi.org/10.1038/cdd.2017.170