Mechanisms of transcriptional regulation by p53

p53 is a transcription factor that suppresses tumor growth through regulation of dozens of target genes with diverse biological functions. The activity of this master transcription factor is inactivated in nearly all tumors, either by mutations in the TP53 locus or by oncogenic events that decrease...

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Detalles Bibliográficos
Autores principales: Sullivan, Kelly D, Galbraith, Matthew D, Andrysik, Zdenek, Espinosa, Joaquin M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729533/
https://www.ncbi.nlm.nih.gov/pubmed/29125602
http://dx.doi.org/10.1038/cdd.2017.174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729533/
https://www.ncbi.nlm.nih.gov/pubmed/29125602
http://dx.doi.org/10.1038/cdd.2017.174

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