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MOMP, cell suicide as a BCL-2 family business

Apoptosis shapes development and differentiation, has a key role in tissue homeostasis, and is deregulated in cancer. In most cases, successful apoptosis is triggered by mitochondrial outer membrane permeabilization (MOMP), which defines the mitochondrial or intrinsic pathway and ultimately leads to...

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Detalles Bibliográficos
Autores principales: Kalkavan, Halime, Green, Douglas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729535/
https://www.ncbi.nlm.nih.gov/pubmed/29053143
http://dx.doi.org/10.1038/cdd.2017.179