BCL-2 family proteins: changing partners in the dance towards death

The BCL-2 family of proteins controls cell death primarily by direct binding interactions that regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible release of intermembrane space proteins, subsequent caspase activation and apoptosis. The affinities and relative a...

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Detalles Bibliográficos
Autores principales: Kale, Justin, Osterlund, Elizabeth J, Andrews, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729540/
https://www.ncbi.nlm.nih.gov/pubmed/29149100
http://dx.doi.org/10.1038/cdd.2017.186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729540/
https://www.ncbi.nlm.nih.gov/pubmed/29149100
http://dx.doi.org/10.1038/cdd.2017.186

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