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BCL-2 family proteins: changing partners in the dance towards death
The BCL-2 family of proteins controls cell death primarily by direct binding interactions that regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible release of intermembrane space proteins, subsequent caspase activation and apoptosis. The affinities and relative a...
Autores principales: | Kale, Justin, Osterlund, Elizabeth J, Andrews, David W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729540/ https://www.ncbi.nlm.nih.gov/pubmed/29149100 http://dx.doi.org/10.1038/cdd.2017.186 |
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