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Dual inhibitors of hepatitis C virus and hepatocellular carcinoma: design, synthesis and docking studies

AIM: Simultaneous inhibition of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) may enhance anti-HCV effects and reduce resistance and side effects. RESULTS/METHODOLOGY: Novel hybrid derivatives were designed and synthesized to exhibit dual activity against HCV and its associated major co...

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Detalles Bibliográficos
Autores principales: El-Miligy, Mostafa MM, Rida, Samia M, Ashour, Fawzia A, Badr, Mona H, El-Bassiony, Ehab M, El-Demellawy, Maha A, Omar, Ashraf M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729604/
https://www.ncbi.nlm.nih.gov/pubmed/29255624
http://dx.doi.org/10.4155/fsoa-2017-0075