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Deletion and downregulation of MTAP contribute to the motility of esophageal squamous carcinoma cells

Esophageal squamous cell carcinoma (ESCC) is among the most common malignancies, with a low 5-year overall survival rate. In previous studies, we and others have found that 9p21.3 was the most frequently deleted region in ESCC. The MTAP gene, which is located close to CDKN2A/B in 9p21.3, encodes met...

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Detalles Bibliográficos
Autores principales: Cheng, Xiao-Yu, Liu, Zou, Shang, Li, Cai, Hong-Qing, Zhang, Yu, Cai, Yan, Xu, Xin, Hao, Jia-Jie, Wang, Ming-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729838/
https://www.ncbi.nlm.nih.gov/pubmed/29270023
http://dx.doi.org/10.2147/OTT.S151953