Biological factors that impinge on Chagas disease drug development

Chagas disease is caused by infection with the insect-transmitted protozoan Trypanosoma cruzi, and is the most important parasitic infection in Latin America. The current drugs, benznidazole and nifurtimox, are characterized by limited efficacy and toxic side-effects, and treatment failures are freq...

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Detalles Bibliográficos
Autores principales: FRANCISCO, AMANDA F., JAYAWARDHANA, SHIROMANI, LEWIS, MICHAEL D., TAYLOR, MARTIN C., KELLY, JOHN M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729846/
https://www.ncbi.nlm.nih.gov/pubmed/28831944
http://dx.doi.org/10.1017/S0031182017001469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729846/
https://www.ncbi.nlm.nih.gov/pubmed/28831944
http://dx.doi.org/10.1017/S0031182017001469

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