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Biological factors that impinge on Chagas disease drug development

Chagas disease is caused by infection with the insect-transmitted protozoan Trypanosoma cruzi, and is the most important parasitic infection in Latin America. The current drugs, benznidazole and nifurtimox, are characterized by limited efficacy and toxic side-effects, and treatment failures are freq...

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Detalles Bibliográficos
Autores principales:	FRANCISCO, AMANDA F., JAYAWARDHANA, SHIROMANI, LEWIS, MICHAEL D., TAYLOR, MARTIN C., KELLY, JOHN M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729846/ https://www.ncbi.nlm.nih.gov/pubmed/28831944 http://dx.doi.org/10.1017/S0031182017001469

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