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Non-immune cells equipped with T cell receptor-like signaling for cancer cell ablation
The ability to engineer custom cell-contact-sensing output devices into human non-immune cells would be useful for extending the applicability of cell-based cancer therapies and avoiding risks associated with engineered immune cells. Here, we have developed a new class of synthetic T-cell receptor-l...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730048/ https://www.ncbi.nlm.nih.gov/pubmed/29131143 http://dx.doi.org/10.1038/nchembio.2498 |