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Convergent downstream candidate mechanisms of independent intergenic polymorphisms between co-classified diseases implicate epistasis among noncoding elements()

Eighty percent of DNA outside protein coding regions was shown biochemically functional by the ENCODE project, enabling studies of their interactions. Studies have since explored how convergent downstream mechanisms arise from independent genetic risks of one complex disease. However, the cross-talk...

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Detalles Bibliográficos
Autores principales: Han, Jiali, Li, Jianrong, Achour, Ikbel, Pesce, Lorenzo, Foster, Ian, Li, Haiquan, Lussier, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730078/
https://www.ncbi.nlm.nih.gov/pubmed/29218911