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Estimated clinical impact of the Xpert MTB/RIF Ultra cartridge for diagnosis of pulmonary tuberculosis: A modeling study

BACKGROUND: The Xpert MTB/RIF (Xpert) assay offers rapid and accurate diagnosis of tuberculosis (TB) but still suffers from imperfect sensitivity. The newer Xpert MTB/RIF Ultra cartridge has shown improved sensitivity in recent field trials, but at the expense of reduced specificity. The clinical im...

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Detalles Bibliográficos
Autores principales: Kendall, Emily A., Schumacher, Samuel G., Denkinger, Claudia M., Dowdy, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730108/
https://www.ncbi.nlm.nih.gov/pubmed/29240766
http://dx.doi.org/10.1371/journal.pmed.1002472