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A low fat diet ameliorates pathology but retains beneficial effects associated with CPT1b knockout in skeletal muscle
Inhibiting fatty acid oxidation is one approach to lowering glucose levels in diabetes. Skeletal muscle specific Carnitine Palmitoyltransferase 1b knockout mice (Cpt1b(m-/-)) comprise a model of impaired fat oxidation; and have decreased fat mass and enhanced glucose disposal and muscle oxidative ca...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730174/ https://www.ncbi.nlm.nih.gov/pubmed/29240830 http://dx.doi.org/10.1371/journal.pone.0188850 |