Ras GAP-related and C-terminal domain-dependent localization and tumorigenic activities of IQGAP1 in melanoma cells

IQGAP1 interacts with a number of binding partners through a calponin homology domain (CHD), a WW motif, IQ repeats, a Ras GAP-related domain (GRD), and a conserved C-terminal (CT) domain. Among various biological and cellular functions, IQGAP1 is known to play a role in actin cytoskeleton dynamics...

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Detalles Bibliográficos
Autores principales: Reimer, Michael, Denby, Elisabeth, Zustiak, Silviya P., Schober, Joseph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730206/
https://www.ncbi.nlm.nih.gov/pubmed/29240845
http://dx.doi.org/10.1371/journal.pone.0189589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730206/
https://www.ncbi.nlm.nih.gov/pubmed/29240845
http://dx.doi.org/10.1371/journal.pone.0189589

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