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Single subject transcriptome analysis to identify functionally signed gene set or pathway activity

Analysis of single-subject transcriptome response data is an unmet need of precision medicine, made challenging by the high dimension, dynamic nature and difficulty in extracting meaningful signals from biological or stochastic noise. We have proposed a method for single subject analysis that uses a...

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Detalles Bibliográficos
Autores principales: Berghout, Joanne, Li, Qike, Pouladi, Nima, Li, Jianrong, Lussier, Yves A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730358/
https://www.ncbi.nlm.nih.gov/pubmed/29218900