The mechanism of variability in transcription start site selection

During transcription initiation, RNA polymerase (RNAP) binds to promoter DNA, unwinds promoter DNA to form an RNAP-promoter open complex (RPo) containing a single-stranded ‘transcription bubble,’ and selects a transcription start site (TSS). TSS selection occurs at different positions within the pro...

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Detalles Bibliográficos
Autores principales: Yu, Libing, Winkelman, Jared T, Pukhrambam, Chirangini, Strick, Terence R, Nickels, Bryce E, Ebright, Richard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730371/
https://www.ncbi.nlm.nih.gov/pubmed/29168694
http://dx.doi.org/10.7554/eLife.32038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730371/
https://www.ncbi.nlm.nih.gov/pubmed/29168694
http://dx.doi.org/10.7554/eLife.32038

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