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Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking
The spatial organization of RNA within cells is a crucial factor influencing a wide range of biological functions throughout all kingdoms of life. However, a general understanding of RNA localization has been hindered by a lack of simple, high-throughput methods for mapping the transcriptomes of sub...
Autores principales: | Kaewsapsak, Pornchai, Shechner, David Michael, Mallard, William, Rinn, John L, Ting, Alice Y |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730372/ https://www.ncbi.nlm.nih.gov/pubmed/29239719 http://dx.doi.org/10.7554/eLife.29224 |
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