A regulatory circuit composed of DNA methyltransferases and receptor tyrosine kinases controls lung cancer cell aggressiveness

Overexpression of DNMT1 and KIT is prevalent in lung cancer, yet the underlying molecular mechanisms are poorly understood. While the deregulated activation of DNMT1 or KIT has been implicated in lung cancer pathogenesis, whether and how DNMT1 and KIT orchestrate lung tumorigenesis are unclear. Here...

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Detalles Bibliográficos
Autores principales: Yan, Fei, Shen, Na, Pang, Jiuxia, Zhao, Na, Deng, Bo, Li, Bing, Yang, Yanan, Yang, Ping, Molina, Julian R., Liu, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730463/
https://www.ncbi.nlm.nih.gov/pubmed/28869603
http://dx.doi.org/10.1038/onc.2017.305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730463/
https://www.ncbi.nlm.nih.gov/pubmed/28869603
http://dx.doi.org/10.1038/onc.2017.305

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