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A non-canonical Notch complex regulates adherens junctions and vascular barrier function

The vascular barrier that separates blood from tissues is actively regulated by the endothelium and is essential for transport, inflammation, and hemostasis(1). Hemodynamic shear stress plays a critical role in maintaining endothelial barrier function(2), but how this occurs remains unknown. Here, u...

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Detalles Bibliográficos
Autores principales: Polacheck, William J., Kutys, Matthew L., Yang, Jinling, Eyckmans, Jeroen, Wu, Yinyu, Vasavada, Hema, Hirschi, Karen K., Chen, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730479/
https://www.ncbi.nlm.nih.gov/pubmed/29160307
http://dx.doi.org/10.1038/nature24998