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A non-canonical Notch complex regulates adherens junctions and vascular barrier function
The vascular barrier that separates blood from tissues is actively regulated by the endothelium and is essential for transport, inflammation, and hemostasis(1). Hemodynamic shear stress plays a critical role in maintaining endothelial barrier function(2), but how this occurs remains unknown. Here, u...
Autores principales: | Polacheck, William J., Kutys, Matthew L., Yang, Jinling, Eyckmans, Jeroen, Wu, Yinyu, Vasavada, Hema, Hirschi, Karen K., Chen, Christopher S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730479/ https://www.ncbi.nlm.nih.gov/pubmed/29160307 http://dx.doi.org/10.1038/nature24998 |
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