Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity

Alzheimer’s disease (AD) is a common and devastating disease characterized by the aggregation of amyloid-β peptide (Aβ), yet we know relatively little about the underlying molecular mechanisms or how to treat AD patients. Here, we provide bioinformatic and experimental evidence of a conserved mitoch...

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Detalles Bibliográficos
Autores principales: Sorrentino, Vincenzo, Romani, Mario, Mouchiroud, Laurent, Beck, John S., Zhang, Hongbo, D’Amico, Davide, Moullan, Norman, Potenza, Francesca, Schmid, Adrien W., Rietsch, Solène, Counts, Scott E., Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730497/
https://www.ncbi.nlm.nih.gov/pubmed/29211722
http://dx.doi.org/10.1038/nature25143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730497/
https://www.ncbi.nlm.nih.gov/pubmed/29211722
http://dx.doi.org/10.1038/nature25143

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