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Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
Alzheimer’s disease (AD) is a common and devastating disease characterized by the aggregation of amyloid-β peptide (Aβ), yet we know relatively little about the underlying molecular mechanisms or how to treat AD patients. Here, we provide bioinformatic and experimental evidence of a conserved mitoch...
Autores principales: | Sorrentino, Vincenzo, Romani, Mario, Mouchiroud, Laurent, Beck, John S., Zhang, Hongbo, D’Amico, Davide, Moullan, Norman, Potenza, Francesca, Schmid, Adrien W., Rietsch, Solène, Counts, Scott E., Auwerx, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730497/ https://www.ncbi.nlm.nih.gov/pubmed/29211722 http://dx.doi.org/10.1038/nature25143 |
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