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Tricellulin is regulated via interleukin 13 receptor α2, affects macromolecule uptake, and is decreased in ulcerative colitis

In the two inflammatory bowel diseases, ulcerative colitis (UC) and Crohn’s disease (CD), altered expression of tight junction (TJ) proteins leads to an impaired epithelial barrier including increased uptake of luminal antigens supporting the inflammation. Here we focused on regulation of tricelluli...

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Detalles Bibliográficos
Autores principales: Krug, SM, Bojarski, C, Fromm, A, Lee, IM, Dames, P, Richter, JF, Turner, JR, Fromm, M, Schulzke, JD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730503/
https://www.ncbi.nlm.nih.gov/pubmed/28612843
http://dx.doi.org/10.1038/mi.2017.52