Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

Cross-presentation is a critical function of dendritic cells (DCs) required for induction of antitumor immune responses and success of cancer immunotherapy. It is established that tumor-associated DCs are defective in their ability to cross-present antigens. However, the mechanisms driving these def...

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Detalles Bibliográficos
Autores principales: Veglia, Filippo, Tyurin, Vladimir A., Mohammadyani, Dariush, Blasi, Maria, Duperret, Elizabeth K., Donthireddy, Laxminarasimha, Hashimoto, Ayumi, Kapralov, Alexandr, Amoscato, Andrew, Angelini, Roberto, Patel, Sima, Alicea-Torres, Kevin, Weiner, David, Murphy, Maureen E., Klein-Seetharaman, Judith, Celis, Esteban, Kagan, Valerian E., Gabrilovich, Dmitry I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730553/
https://www.ncbi.nlm.nih.gov/pubmed/29242535
http://dx.doi.org/10.1038/s41467-017-02186-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730553/
https://www.ncbi.nlm.nih.gov/pubmed/29242535
http://dx.doi.org/10.1038/s41467-017-02186-9

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