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Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer
Cross-presentation is a critical function of dendritic cells (DCs) required for induction of antitumor immune responses and success of cancer immunotherapy. It is established that tumor-associated DCs are defective in their ability to cross-present antigens. However, the mechanisms driving these def...
| Autores principales: | , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730553/ https://www.ncbi.nlm.nih.gov/pubmed/29242535 http://dx.doi.org/10.1038/s41467-017-02186-9 |