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Mis-expression of grainyhead-like transcription factors in zebrafish leads to defects in enveloping layer (EVL) integrity, cellular morphogenesis and axial extension
The grainyhead-like (grhl) transcription factors play crucial roles in craniofacial development, epithelial morphogenesis, neural tube closure, and dorso-ventral patterning. By utilising the zebrafish to differentially regulate expression of family members grhl2b and grhl3, we show that both genes r...
Autores principales: | Miles, Lee B., Darido, Charbel, Kaslin, Jan, Heath, Joan K., Jane, Stephen M., Dworkin, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730563/ https://www.ncbi.nlm.nih.gov/pubmed/29242584 http://dx.doi.org/10.1038/s41598-017-17898-7 |
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