Atorvastatin inhibits cholesterol-induced caspase-3 cleavage through down-regulation of p38 and up-regulation of Bcl-2 in the rat carotid artery

AIM: Atherosclerotic lesions in the carotid arteries lead to a broad range of cerebrovascular disorders such as vascular dementia and ischaemic stroke. Recent studies have verified the beneficial role of atorvastatin (AV) in atherosclerosis. Despite a large body of studies, the mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Bayatmakoo, Roshanak, Yaghmaei, Parichehreh, Rashtchizadeh, Nadereh, Farhoudi, Mehdi, Karimi, Pouran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinics Cardive Publishing 2017
Materias:
Cardiovascular Topics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730680/
https://www.ncbi.nlm.nih.gov/pubmed/28498386
http://dx.doi.org/10.5830/CVJA-2017-005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730680/
https://www.ncbi.nlm.nih.gov/pubmed/28498386
http://dx.doi.org/10.5830/CVJA-2017-005

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