Cargando…

Atorvastatin inhibits cholesterol-induced caspase-3 cleavage through down-regulation of p38 and up-regulation of Bcl-2 in the rat carotid artery

AIM: Atherosclerotic lesions in the carotid arteries lead to a broad range of cerebrovascular disorders such as vascular dementia and ischaemic stroke. Recent studies have verified the beneficial role of atorvastatin (AV) in atherosclerosis. Despite a large body of studies, the mechanisms underlying...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bayatmakoo, Roshanak, Yaghmaei, Parichehreh, Rashtchizadeh, Nadereh, Farhoudi, Mehdi, Karimi, Pouran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Clinics Cardive Publishing 2017
Materias:	Cardiovascular Topics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730680/ https://www.ncbi.nlm.nih.gov/pubmed/28498386 http://dx.doi.org/10.5830/CVJA-2017-005

Ejemplares similares

Moderate Aerobic Training Inhibits Middle-Aged Induced Cardiac Calcineurin-NFAT Signaling by Improving TGF-ß, NPR-A, SERCA2, and TRPC6 in Wistar Rats
por: Baghaiee, Behrouz, et al.
Publicado: (2021)

Effects of Selenium in the MAPK Signaling Cascade
por: Rashtchizadeh, Nadereh, et al.
Publicado: (2015)

Comparative effects of quercetin and hydroalcoholic extract of Otostegia persica boiss with atorvastatin on atherosclerosis complication in male wistar rats
por: Parvin, Ali, et al.
Publicado: (2019)

Investigation of Supercharging as A Strategy to Enhance the Solubility and Plasminogen Cleavage Activity of Reteplase
por: Seyedhosseini Ghaheh, Hooria, et al.
Publicado: (2020)

Pharmacological Targeting of Bcl-2 Induces Caspase 3-Mediated Cleavage of HDAC6 and Regulates the Autophagy Process in Colorectal Cancer
por: Yang, Donglin, et al.
Publicado: (2023)

ASCOT analysis with atorvastatin shows limits of CRP as indicator of cardiovascular risk
Publicado: (2011)

The effects of treatment with atorvastatin versus rosuvastatin on endothelial dysfunction in patients with hyperlipidaemia
por: Vahit, Demir, et al.
Publicado: (2018)

Amlodipine + atorvastatin single pill is the most effective choice for primary prevention
por: Aalbers, J
Publicado: (2010)

Mimicking Cdk2 phosphorylation of Bcl-xL at Ser73 results in caspase activation and Bcl-xL cleavage
por: Seng, NS, et al.
Publicado: (2016)

Protection of renal damage by HMG-CoA inhibitors: A comparative study between atorvastatin and rosuvastatin
por: Jabarpour, Maryam, et al.
Publicado: (2020)

Carotid artery stump pressure and associated neurological changes in predominantly symptomatic carotid artery disease patients undergoing awake carotid endarterectomy
por: Rajaruthnam, P, et al.
Publicado: (2009)

Cleavage-Mediated Regulation of Myd88 Signaling by Inflammasome-Activated Caspase-1
por: Avbelj, Monika, et al.
Publicado: (2022)

Autophagy Regulates the Post-Translational Cleavage of BCL-2 and Promotes Neuronal Survival
por: Lossi, Laura, et al.
Publicado: (2010)

Cholesterol metabolism—physiological regulation and pathophysiological deregulation by the endoplasmic reticulum
por: Röhrl, Clemens, et al.
Publicado: (2018)

Subclavian Artery-Carotid Artery Bypass for Subclavian Artery or Common Carotid Artery Severe Stenosis or Occlusion
por: YAMAGUCHI, Koji, et al.
Publicado: (2023)

Bcl-2–regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9
por: Marsden, Vanessa S., et al.
Publicado: (2004)

An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation
por: Turowec, Jacob P., et al.
Publicado: (2014)

Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate
por: Aries, A, et al.
Publicado: (2014)

Regulation of Caspase-3 and Bcl-2 Expression in Dalton's Lymphoma Ascites Cells by Abrin
por: Ramnath, V., et al.
Publicado: (2009)

Regulation of Apelin-13 on Bcl-2 and Caspase-3 and Its Effects on Adipocyte Apoptosis
por: Li, Zhan, et al.
Publicado: (2021)

The road to death: Caspases, cleavage, and pores
por: Dixit, Vishva M.
Publicado: (2023)

Carotid intervention: stent or surgery? A prospective audit
por: Robbs, JV, et al.
Publicado: (2009)

Thymoquinone recovers learning function in a rat model of Alzheimer’s disease
por: Poorgholam, Parvin, et al.
Publicado: (2018)

Clinical significance of checkpoint regulator “Programmed death ligand-1 (PD-L1)” expression in meningioma: review of the current status
por: Karimi, Shirin, et al.
Publicado: (2021)

Caspases and p38 MAPK Regulate Endothelial Cell Adhesiveness for Mesenchymal Stem Cells
por: Potapova, Irina A., et al.
Publicado: (2013)

Carotid characteristics of black South Africans with five-year sustained hypertension
por: Maritz, Melissa, et al.
Publicado: (2016)

Carotid artery type of Eagle syndrome: an uncommon cause of ischemic stroke
por: Lakner, Katarina, et al.
Publicado: (2022)

Cymene and Metformin treatment effect on biochemical parameters of male NMRI mice fed with high fat diet
por: Lotfi, Peyman, et al.
Publicado: (2015)

Thymoquinone ameliorates some endocrine parameters and histological alteration in a rat model of polycystic ovary syndrome
por: Taghvaee Javanshir, Sima, et al.
Publicado: (2018)

Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis
por: Mazroui, Rachid, et al.
Publicado: (2008)

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma
por: Keuper, M, et al.
Publicado: (2013)

Effect of Nandrolone Decanoate on Serum Lipoprotein (a) and its isoforms in hemodialysis patients
por: Ghorbanihaghjo, Amir, et al.
Publicado: (2004)

The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins
por: Marzo, Isabel, et al.
Publicado: (1998)

Differentiation of Definitive Endoderm from Human Induced Pluripotent Stem Cells on hMSCs Feeder in a Defined Medium
por: Jaafarpour, Zahra, et al.
Publicado: (2016)

Male Idiopathic Hypogonadotropic Hypogonadism: Serum Insulin-like Growth Factor-1 and Oestradiol Levels
por: Salehisedeh, Nastaran, et al.
Publicado: (2022)

Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio
por: Yi, Jingwen, et al.
Publicado: (2015)

Simultaneous coronary artery bypass grafting and carotid endarterectomy can be performed with low mortality rates
por: Aydin, Ebuzer, et al.
Publicado: (2014)

Effect of hypothermia in patients undergoing simultaneous carotid endarterectomy and coronary artery bypass graft surgery
por: Ozen, Yucel, et al.
Publicado: (2015)

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8
por: Chacko, Alex D, et al.
Publicado: (2010)

Caspase-8 auto-cleavage regulates programmed cell death and collaborates with RIPK3/MLKL to prevent lymphopenia
por: Li, Xiaoming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gfldsbmslafkggqj5sdvd4u679