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Pomegranate extract inhibits EMT in clear cell renal cell carcinoma in a NF-κB and JNK dependent manner

OBJECTIVE: Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC) and is characterized by biallelic inactivation of the von Hippel-Lindau (VHL) tumor suppressor gene. One effect of VHL inactivation is hypoxia inducible factor alpha (HIFα)-independent constit...

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Detalles Bibliográficos
Autores principales: An, Jiabin, Guo, Yanchuan, Wang, Ting, Pantuck, Allan J., Rettig, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730684/
https://www.ncbi.nlm.nih.gov/pubmed/29264118
http://dx.doi.org/10.1016/j.ajur.2015.04.009