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Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles

Efficient antiviral immunity requires interference with virus replication at multiple layers targeting diverse steps in the viral life cycle. We describe here a novel flavivirus inhibition mechanism that results in interferon-mediated obstruction of tick-borne encephalitis virus particle assembly an...

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Detalles Bibliográficos
Autores principales: Vonderstein, Kirstin, Nilsson, Emma, Hubel, Philipp, Nygård Skalman, Larsård, Upadhyay, Arunkumar, Pasto, Jenny, Pichlmair, Andreas, Lundmark, Richard, Överby, Anna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730767/
https://www.ncbi.nlm.nih.gov/pubmed/29046456
http://dx.doi.org/10.1128/JVI.01751-17