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Specific bone region localization of osteolytic versus osteoblastic lesions in a patient-derived xenograft model of bone metastatic prostate cancer

OBJECTIVE: Bone metastasis occurs in up to 90% of men with advanced prostate cancer and leads to fractures, severe pain and therapy-resistance. Bone metastases induce a spectrum of types of bone lesions which can respond differently to therapy even within individual prostate cancer patients. Thus, t...

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Detalles Bibliográficos
Autores principales: Hirata, Takeshi, Park, Seung Chol, Muldong, Michelle T., Wu, Christina N., Yamaguchi, Tomonori, Strasner, Amy, Raheem, Omer, Kumon, Hiromi, Sah, Robert L., Cacalano, Nicholas A., Jamieson, Catriona H.M., Kane, Christopher J., Masuda, Koichi, Kulidjian, Anna A., Jamieson, Christina A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730873/
https://www.ncbi.nlm.nih.gov/pubmed/29264191
http://dx.doi.org/10.1016/j.ajur.2016.09.001