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Prognostic significance of RBP2-H1 variant of JARID1B in melanoma

BACKGROUND: Histone demethylase JARID1B plays several context dependent roles in epigenetic regulation of cellular differentiation in normal development and is highly expressed in multiple human cancers. The protein is a strong transcriptional repressor capable of downregulating numerous genes. Ther...

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Detalles Bibliográficos
Autores principales: Kuźbicki, Łukasz, Lange, Dariusz, Stanek-Widera, Agata, Chwirot, Barbara W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731204/
https://www.ncbi.nlm.nih.gov/pubmed/29246117
http://dx.doi.org/10.1186/s12885-017-3836-x