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Azacitidine improves clinical outcomes in older patients with acute myeloid leukaemia with myelodysplasia-related changes compared with conventional care regimens

BACKGROUND: Compared with World Health Organization-defined acute myeloid leukaemia (AML) not otherwise specified, patients with AML with myelodysplasia-related changes (AML-MRC) are generally older and more likely to have poor-risk cytogenetics, leading to poor response and prognosis. More than one...

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Detalles Bibliográficos
Autores principales: Seymour, John F., Döhner, Hartmut, Butrym, Aleksandra, Wierzbowska, Agnieszka, Selleslag, Dominik, Jang, Jun Ho, Kumar, Rajat, Cavenagh, James, Schuh, Andre C., Candoni, Anna, Récher, Christian, Sandhu, Irwindeep, del Castillo, Teresa Bernal, Al-Ali, Haifa Kathrin, Falantes, Jose, Stone, Richard M., Minden, Mark D., Weaver, Jerry, Songer, Steve, Beach, C. L., Dombret, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731212/
https://www.ncbi.nlm.nih.gov/pubmed/29241450
http://dx.doi.org/10.1186/s12885-017-3803-6