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Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut

Autophagy is critical for homeostasis and cell survival during stress, but can also lead to cell death, a little understood process that has been shown to contribute to developmental cell death in lower model organisms, and to human cancer cell death. We recently reported(1) on our thorough molecula...

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Detalles Bibliográficos
Autores principales: Dasari, Santosh K., Schejter, Eyal, Bialik, Shani, Shkedy, Aya, Levin-Salomon, Vered, Levin-Zaidman, Smadar, Kimchi, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731414/
https://www.ncbi.nlm.nih.gov/pubmed/28933588
http://dx.doi.org/10.1080/15384101.2017.1380134