p53 binding sites in normal and cancer cells are characterized by distinct chromatin context

The tumor suppressor protein p53 interacts with DNA in a sequence-dependent manner. Thousands of p53 binding sites have been mapped genome-wide in normal and cancer cells. However, the way p53 selectively binds its cognate sites in different types of cells is not fully understood. Here, we performed...

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Detalles Bibliográficos
Autores principales: Bao, Feifei, LoVerso, Peter R., Fisk, Jeffrey N., Zhurkin, Victor B., Cui, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731425/
https://www.ncbi.nlm.nih.gov/pubmed/28820292
http://dx.doi.org/10.1080/15384101.2017.1361064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731425/
https://www.ncbi.nlm.nih.gov/pubmed/28820292
http://dx.doi.org/10.1080/15384101.2017.1361064

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