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Transcriptional consequences of XPA disruption in human cell lines

Nucleotide excision repair (NER) in mammalian cells requires the xeroderma pigmentosum group A protein (XPA) as a core factor. Remarkably, XPA and other NER proteins have been detected by chromatin immunoprecipitation at some active promoters, and NER deficiency is reported to influence the activate...

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Detalles Bibliográficos
Autores principales: Manandhar, Mandira, Lowery, Megan G., Boulware, Karen S., Lin, Kevin H., Lu, Yue, Wood, Richard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731452/
https://www.ncbi.nlm.nih.gov/pubmed/28704716
http://dx.doi.org/10.1016/j.dnarep.2017.06.028